What this does
The stocked blend is 20 mg total: 10 mg BPC-157 and 10 mg TB-500. In 3 mL that is 6.67 mg/mL of total peptide and 3.33 mg/mL of each compound. Run the calculator on the compound you are targeting, then read the same volume against the other one, because both arrive together.
The vial size above is the one Peptriva ships, read from the live listing. Change it if yours differs. The dose stays whatever you set — this tool does not suggest one.
What is in a BPC-157 and TB-500 blend vial?
The stocked vial is 20 mg co-lyophilized as 10 mg BPC-157 plus 10 mg TB-500 — a 1:1 ratio, fixed at manufacture and not adjustable afterwards.
The table below uses the 20 mg total. Halve every concentration to get the per-compound figure, because the ratio is 1:1:
| Water added | Concentration | Units for a 1 mg draw |
|---|---|---|
| 1 mL | 20 mg/mL | 5.0 units |
| 2 mL | 10 mg/mL | 10.0 units |
| 3 mL | 6.66667 mg/mL | 15.0 units |
| 5 mL | 4 mg/mL | 25.0 units |
Those are TOTAL peptide concentrations. At 3 mL the vial is 6.67 mg/mL of blend, which is 3.33 mg/mL of BPC-157 and 3.33 mg/mL of TB-500.
Neither compound has an established dose
BPC-157 has three human pilot reports, none dose-finding and none subcutaneous. TB-500 has no published human dose at all. So there is nothing to reconstruct a blend dose from, and the tool does not attempt one.
What the arithmetic can tell you is what a given draw delivers of each. The BPC-157 dosage guide and the TB-500 guide cover what each was administered at separately, and the blend guide covers the combination.
BPC-157 vs TB-500 is worth reading if the question behind the calculation is whether the blend is the right format at all.
The trap on this one: the ratio is not yours to set
People reach for a blend calculator expecting to dial in one compound. A co-lyophilized cake does not work that way.
Draw less and both fall together. Draw more and both rise together. If you titrate to BPC-157 you are simultaneously titrating TB-500, and there is no draw volume that changes one without the other.
That also makes single-variable work impossible, which is worth weighing against the convenience of one reconstitution instead of two. The blend mechanism page covers the rationale for combining them, and the sourcing guide covers buying them separately instead.
Frequently asked questions
How much water for a 20 mg BPC-157 TB-500 blend vial?
Your choice. 3 mL gives 6.67 mg/mL of total peptide, which is 3.33 mg/mL of each compound at the 1:1 ratio. The vial holds the same 20 mg regardless.
How do I calculate the dose of just one compound in the blend?
Run the calculator on the compound you are targeting, then read the same volume against the other. Because the ratio is fixed at 1:1, a draw delivering 250 mcg of BPC-157 delivers 250 mcg of TB-500 at the same time.
Can I adjust one compound in a blend?
No. Both are in a single lyophilized cake at a ratio set at manufacture. Any change to the draw volume moves both together. Buying the two compounds separately is the only way to vary them independently.
What is the correct blend dose?
There isn't one. BPC-157 has three human pilot reports, none dose-finding, and TB-500 has no published human dose. This tool converts what you enter rather than proposing a figure nothing published would support.
References
- American Society of Health-System Pharmacists (ASHP). Handbook on Injectable Drugs: Benzyl alcohol preservative compatibility and stability data. https://www.ashp.org/products-and-services/database-tools/handbook-on-injectable-drugs
- United States Pharmacopeia. (2024). Bacteriostatic Water for Injection — monograph and in-use stability guidance. USP-NF. (See institutional access.) https://doi.org/10.4135/9781412963855.n1200
- Wang, W. (1999). Instability, stabilization, and formulation of liquid protein pharmaceuticals. International Journal of Pharmaceutics, 185(2), 129–188. https://doi.org/10.1016/s0378-5173(99)00152-0
The arithmetic needs no citation; the diluent and stability guidance does.